Has Russia found a cure for COVID19?!

The current worldwide upsurge of COVID-19 is becoming a matter of tremendous concern. The spread of novel coronavirus has brought daily life activities to a standstill. And till date, the best way we have to keep ourselves safe consist only of preventive measures. Therefore, many organizations are working towards formulation of a vaccine and we are also getting positive results. Of the 19 vaccines currently in human trial, only two are in final phase-III; one by China’s Sinopharm and other by AstraZeneca and University of Oxford (announced to be most advanced by WHO). Currently, the researchers from Sechenov University, Russia claim to have developed a clinically safe vaccine against coronavirus. However, WHO still lists Russian COVAX in Phase-I of clinical trial.

Study:

The genomic sequences of coronavirus shows that the S-protein present on the viral surface is the ideal target for vaccine. The concerns for the development of an effective vaccine are the prospects of the virus mutating and waning of the antibody response. The infection with human coronavirus does not always produce long-lived antibody responses and thus chances of re-infection are likely. Apart from this vaccines will also have to undergo clinical and safety trial before being approved.

Theory:

As per the results of preliminary tests, the Russian Vaccine results in an increase in non-specific immunity. The vaccine is administered in two doses and consist of two serotypes (serologically distinguishable strain of microbe) of the human adenovirus, each carrying an S-antigen of the new coronavirus, which enter human cells and produce an immune response. The vaccine showed good results on primates.